Drug toxicity is a major concern in the pharmaceutical industry. It is essential to identify potential toxic effects of drug candidates before they are tested in vivo. Animal testing has been the traditional method for predicting drug toxicity, but it is expensive, time-consuming, and raises ethical concerns. In vitro models have emerged as an alternative to animal testing, but they have limitations in accurately predicting drug toxicity. HUREL® Micro Livers are a breakthrough in vitro model that can predict drug toxicity with superior accuracy and reliability.
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HUREL® Micro Livers are self-assembling co-cultures of primary cryopreserved hepatocytes combined with a non-parenchymal stromal cell line. They are created by allowing the hepatocytes to spontaneously self-assemble into colonies. HUREL® Micro Livers are more accurate and reliable in predicting drug toxicity compared to other in vitro models due to their superior metabolic competency and long-enduring phenotypic stability. They can identify specific toxic effects such as hepatotoxicity and cytotoxicity in drug candidates.
The use of HUREL® Micro Livers reduces the need for animal testing. Animal testing is expensive, time-consuming, and raises ethical concerns. HUREL® Micro Livers can provide more reliable data than animal testing. They can predict drug toxicity with greater accuracy and reliability. HUREL® Micro Livers can also reduce the cost of drug development by reducing the need for animal testing.
In conclusion, HUREL® Micro Livers are a breakthrough in vitro model that can predict drug toxicity with superior accuracy and reliability. They can identify specific toxic effects such as hepatotoxicity and cytotoxicity in drug candidates. The use of HUREL® Micro Livers reduces the need for animal testing and provides more reliable data than other in vitro models. HUREL® Micro Livers are a cost-effective and ethical alternative to animal testing. Visikol’s contract research services can help pharmaceutical companies accelerate the drug discovery and development process by providing advanced tissue imaging and advanced cell culture services. If you’re interested in learning more, please reach out to a member of our team today!