HUREL® Resources

HUREL® Resources2022-03-09T10:26:40-05:00

Resources

Client Feedback

“The HUREL® co-culture can be applied to accurately estimate intrinsic clearance of slowly metabolized drugs and is now utilized as a standard method for in vivo clearance predictions of such compounds in-house.”

–  AstraZeneca, Molecular Pharmaceutics

“In our studies evaluating four low-turnover drugs, the HUREL® co-culture model generated a more robust metabolite profile over seven days than was observed following incubation using hepatocyte suspension.”

–   Q2 Solutions, Drug Metabolism & Disposition

Videos

Clarinex®: The Hunt for the Unproducible Metabolite

Interspecies Comparison of DMPK Endpoints

Blogs

Improved Prediction of Hepatotoxicity (or DILI) Using HUREL® Hepatic Co-cultures

Lab Photo

HUREL® Microliver Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds

Lab Photo 2

Publications