Tumor Microenvironment Panel
To take an in-depth look into the complex and dynamic ecosystem of the tumor microenvironment, a 19-marker panel allows for a detailed analysis of various cell populations, activation status and characteristics of the surrounding microenvironment of tumor tissue. Macrophage polarization and T-cell phenotype markers allows for an overview of polarization status (M1, M2a, M2b, M2c and M2d) and T-cell populations (Helper, Cytotoxic and Regulatory). Activation status of fibroblasts status with FAP and Vimentin associated with common fibroblasts markers and profile markers for proliferation (Ki67), apoptosis (Caspase-3), angiogenesis (VEGF) and hypoxia (HIF1α) allow an assessment of tumor progression, severity, and changes within the extracellular matrix of a tumor.
DAPI/Blue, CD206/Yellow, CD8/Red, VEGF/Green, CD45/CY5