Adopt tissue clearing into your research quickly and easily.

We have developed Visikol® HISTO™ as the first commercially available, easy-to-use, non-destructive and rapid 3D histology platform. With Visikol HISTO you are able to visualize biological tissues in 3D by pairing the rapid clearing of Visikol HISTO with fluorescent labeling. 

Benefits of Visikol HISTO

  • Rapid tissue clearing

  • Easy-to-use

  • No special equipment required

  • Compatible with IF, FP and other fluorescent labels

  • Affordable for all researchers

  • Customized protocols for all applications

  • Reversible for follow up 2D H&E/IHC

  • Non-destructive to morphology


Build a customized protocol for your application

We have worked with over 400 research labs from around the world to develop protocol guidance for every application.

Why Visikol HISTO for tissue clearing? 

There are several tissue clearing techniques that have been developed over the last few years (tissue clearing overview) each of which have unique advantages and disadvantages. However, the adoption of tissue clearing into research as a reliable tool for bio-imaging has been rather limited, as each technique requires specific adaptations for differing tissue types, labels, fixation methods, imaging modalities and custom microscope objectives.

Visikol Inc. has developed the Visikol HISTO technology in collaboration with over 400 research labs across the US and EU, and have built the Visikol HISTO Protocol Guidebook to ensure that tissue clearing is easy to adopt for all applications. Visikol HISTO is easy-to-use, rapid, and affordable. Furthermore, Visikol HISTO provides reversible clearing, which means that 3D data can be validated against traditional histology.

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