Simplify  tissue clearing with Visikol® HISTO™


Mammary tumor labeled with Ki67

Mammary tumor labeled with Ki67

Mouse prostate tumor vasculature

Mouse prostate tumor vasculature

Mouse brain labeled for anti-Zika

Mouse brain labeled for anti-Zika

Owl brain connectomics

Owl brain connectomics

Mouse brain labeled with NeuN and DAPI

Mouse brain labeled with NeuN and DAPI

Healthy mammary tissue

Healthy mammary tissue


Adopt tissue clearing into your research quickly and easily


  • Rapid tissue clearing
  • Easy-to-use
  • No special equipment required
  • Affordable for all researchers
  • Compatible with IF, FP and other fluorescent labels
  • Customized protocols for all applications
  • Reversible for follow up 2D H&E/IHC
  • Non-destructive to morphology

We have developed Visikol HISTO as the market's first easy-to-use, non-destructive and rapid 3D histology platform. With Visikol HISTO you are able to visualize biological tissues in 3D by pairing the rapid clearing of Visikol HISTO with fluorescent labeling.  


Why Visikol HISTO for tissue clearing? 


There are dozens of tissue clearing techniques that have been developed over the last few years (tissue clearing overview) which have their unique advantages and disadvantages. However, researchers have had a significant challenge with adopting tissue clearing into their research as each technique requires adaptation for every tissue type, label, fixation method, imaging modality and objective.

Visikol developed the Visikol HISTO technology in collaboration with over 400 research labs and have built the Visikol HISTO protocol builder to make tissue clearing easy to adopt for all applications. Outside of its ease-of-use, Visikol HISTO is rapid, affordable and also is reversible which means that 3D data can be compared to traditional histological sections taken after 3D imaging. 

 

Build a customized protocol for your application

We have worked with over 400 research labs from around the world to develop a protocol builder web app that lets researchers design a protocol for their specific application.