Advanced in vitro models, such as our liver fibrosis model, are known to provide a more efficient and cost-effective way to screen potential drug candidates, accelerating the drug discovery process. In vitro models are cell culture models are used to screen potential drug candidates and evaluate their efficacy and safety before moving on to animal and human trials. These models have become increasingly popular in recent years, due to their ability to reduce the cost and time associated with drug discovery and development.
3D Cell Culture Liver Fibrosis Model
Our liver fibrosis assay uses 3D cell culture models that incorporate a mixture of hepatocytes or hepatocyte-like cells with nonparenchymal cells (NPCs) to provide the greatest utility. This method provides a more accurate representation of the in vivo environment and allows for the evaluation of multiple genes at once. The assay analyzes gene expression via qPCR, allowing for many genes of interest to be evaluated using a single sample.
3D cell culture models offer several benefits in drug discovery, including better mimicking of the in vivo microenvironment and gene expression of tissues, providing a method for improving in vitro studies used in drug discovery and development. They also allow for the evaluation of multiple genes at once and can be customized to meet specific research requirements. Nonparenchymal cells are incorporated into 3D cell culture models to better mimic the in vivo microenvironment and gene expression of tissues. This is important because it provides a more accurate representation of the in vivo environment and allows for more accurate evaluation of drug candidates.
qPCR Analysis
qPCR is a method used to analyze gene expression in 3D cell culture models. It allows for the evaluation of multiple genes at once using a single sample, providing a more efficient and cost-effective method for evaluating drug candidates. Our liver fibrosis assay uses qPCR to analyze gene expression, providing researchers with a more comprehensive understanding of the effects of potential drug candidates.
Why Work With Us?
Our quality control process in place for all new cell and control compound lots to ensure standardization of their liver assays. We also validate our assays using multiple methods to ensure accuracy and reliability. This ensures consistent and reliable results, providing researchers with the confidence they need to move forward with drug discovery and development.
Advanced in vitro models contribute to the efficiency and cost-effectiveness of drug discovery by providing a more accurate representation of the in vivo environment, allowing for the evaluation of multiple genes at once, and reducing the need for animal and human trials. There are several examples of drugs that have been discovered using advanced in vitro models, including drugs for cancer, liver disease, and other conditions.
Advanced in vitro models provide a more efficient and cost-effective way to screen potential drug candidates, accelerating the drug discovery process. These models offer several benefits, including better mimicking of the in vivo microenvironment and gene expression of tissues, providing a method for improving in vitro studies used in drug discovery and development. Our liver fibrosis assay provides researchers with consistent and reliable results, ensuring the confidence needed to move forward with drug discovery and development. To learn more about this assay, reach out to a member of our team to get started today!