LC-MS/MS Quantification of the Methylation Status of Clinical Samples of NASH Liver Tissues
Nonalcoholic fatty liver disease (NAFLD) is a common hepatic disorder in individuals who drink little or no alcohol. A [...]
Carol Tomaszewski2022-09-09T07:41:23-05:00Tags: epigenetics, LC-MS/MS, Liver, Methylation, NASH|
Nonalcoholic fatty liver disease (NAFLD) is a common hepatic disorder in individuals who drink little or no alcohol. A [...]
Carol Tomaszewski2022-08-04T13:56:00-05:00Tags: biomarker, bisulfite conversion, cell painting, drug discovery, epigenetic, Gene specific methylation, gene-methylation, gene-promoter methylation, Global DNA methylation, LC-MS/MS, P53, PCR, tumor suppressive genes|
DNA methylation is a critical epigenetic modification that controls gene expression and genome stability, which has oncogenic implications during [...]
Carol Tomaszewski2022-10-06T14:01:31-05:00Tags: DNA Methylation, LC-MS/MS|
DNA methylation in mammals occurs at the 5-position of the nitrogen base, cytosine, typically at CpG dinucleotide islands, to [...]
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