Corning and Visikol Team Up for Webinar on 3D Imaging of 3D Cell Culture Models

Join us on May 17th at 12:00 PM EST

One of the obstacles to working with 3D cell cultures is how to extract meaningful data from them. To address this problem, Visikol has developed their Visikol® HISTO-M™ tissue clearing reagent that allows for complete 3D cell culture characterization using confocal imaging or a 3-fold increase in cells detected using wide-field microscopy. This tissue clearing approach has been developed to be rapid and compatible with multi-well plates so that it can be conducted using automated pipetting robots and high content confocal imaging systems.

By attending this webinar you will learn about:
• Methods to enable 3D cell culture
• Ways to enhance imaging and characterization of 3D spheroids

Presenter Bios:

Dr. Tom Villani is the CSO and Co-founder of Visikol Inc and is responsible for the companies scientific strategy. Since launching Visikol with Co-Founders Dr. Michael Johnson and Nick Crider, Dr. Villani has led the development of the Visikol HISTO tissue clearing technology for three-dimensional tissue imaging as well as a suite of digital pathology tools. Visikol has leveraged these technologies in its 3Screen service offering where the company is focused on transforming tissues into actionable insights as a service for primarily pharmaceutical companies. 

Dr. Ann Rossi graduated from the University of Rochester School of Medicine and Dentistry with a Ph.D. in Pharmacology and received postdoctoral training at the University of Chicago. Prior to joining Corning, Ann worked as a Senior Scientist at ARMGO Pharma, Inc., a small private pharmaceutical company, contributing her expertise in calcium signaling toward developing new assays for the company’s screening cascade. Ann is new to Corning Life Sciences as the Applications Lab Manager in Kennebunk, Maine and is drawing on her strong academic and industry research experience to direct the activities of the applications group.

Visikol and Corning

Come Visit Visikol at Society of Toxicology 2018 in San Antonio at Booth 1718!

Visikol is focused on transforming tissues into actionable insights and has developed a wide-range of imaging tools, reagents and services. At SOT, Visikol will be discussing how best to leverage 3D in vitro cell culture models for toxicity assays, advanced optical projection tomography for use in DART studies and how the Visikol® HISTO™ technology can be used to more completely study tissues.

Come by stop by the Visikol booth at booth 1718 in the ToxExpo or check out one of our posters:

Visikol Posters


  • Mon Mar 12 3:00 to 4:30 PM: 1132: P169: Measuring Traumatic Brain Injury in Rat Models Using Tissue Clearing and 3D Histology
  • Tue Mar 13 3:00 to 4:30 PM: 2144: P481: Optical Projection Tomography with a Tissue-Clearing Agent for Developmental and Reproductive Toxicology Studies
  • Tue Mar 13 3:00 to 4:30 PM: 2131: P468: Improved Characterization of Compound Toxicity through the Application of a Tissue-Clearing Technique to 3D In Vitro Model Screening
  • Thu Mar 15 8:30 to 11:30 PM: 3320: P101: 3D Histological Characterization of Precision-Cut Lung Slices for Inhalation Studies


Visikol SOT 2018 San Antonio Logo

Visikol selected for SLAS Innovation AveNEW

Visikol was selected to present at the Society for Laboratory Automation and Screening in February at the SLAS Innovation AveNEW which highlights some of the most innovative companies in the automation and screening space. 

Visikol will be exhibiting along with Automation Trainer LLCBenchlingCell X TechnologiesCenso BiotechnologiesThe Genomic Automation Companyiota Sciences and VasculoTox, Inc.

At SLAS, Visikol will be showcasing its 3D in vitro drug discovery services as well as its Visikol HISTO-M technology. 

For more info: Innovation AveNEW at SLAS

Visikol Innovation AveNEW SLAS

Visikol Selected for LRIG Rapid-Fire Innovation Session at SLAS

On Monday February 5th from 6:00 - 8:00 PM PST Visikol will be participating in the late night LRIG Rapid-Fire Innovation Session at the Society for Laboratory Automation and Screening conference in San Diego at the San Diego Convention Center in Room 8. Come listen to Dr. Villani discuss how the Visikol HISTO-M technology can be used to improve your 3D cell culture in vitro assays.  

Late Night with LRIG: Rapid-Fire Innovation Session

LRIG Selects Visikol to Present

Visikol HISTO Tissue Clearing Workshop

On January 26th, Visikol is running a tissue clearing workshop at Florida Atlantic University where the Visikol team will give an overview of tissue clearing, 3D microscopy, whole mount immunolabeling and data processing. The tissue clearing workshop will be comprised of a short presentation followed by a demo where the Visikol team will help researchers prep their samples for 3D tissue imaging. The tissue clearing workshop will focus on several key aspects of 3D tissue imaging and dispelling several key myths. 

  • Secrets of success - how to dramatically improve your results and reduce optimization time and cost. 
  • Choosing the right microscope and objective - what is required for your research question.
  • Why choose one tissue clearing technique over another.
  • Whole mount immunolabeling and fluorescent protein compatibility.
  • How to validate 3D tissue imaging results.
  • How thick of a tissue should you use for your research questions.
  • Tissue clearing for use with 3D cell culture models (e.g. organoids, microtissues, spheroids).
  • Sample preparation for optimal results. 
  • 3D microscopy data processing and virtual reality visualization. 

Many researchers have struggled with implementing tissue clearing into their research for a wide-range of reasons and it is the focus of the Visikol team to reduce this adoption hurdle. Visikol is committed to making tissue clearing and 3D tissue imaging easy and accessible to all researchers through the Visikol HISTO platform. 

If you are interested in hosting a tissue clearing and 3D microscopy demo at your university reach out to the Visikol team at:

tdtomato mouse brain cleared with Visikol HISTO

Come visit Visikol at SLAS 2018

The 2018 Society for Laboratory Automation and Screening (SLAS) conference will be held in San Diego from Feb 3-7th this year and Visikol will be at booth #1829. Visikol will also be presenting several posters as well as a tutorial on 3D cell culturing and high content screening with Corning

Tutorial Presentations

Monday, February 5th 2:00 - 2:45 PM - Room 1B - 3D Image-based Characterization of 3D Cell Culture Models Using Spheroid Microplates.


Monday, February 5th, 5:00 - 6:00 PM - 1036-B- Combination of Ultra-Low Attachment Spheroid Plates with a Tissue Clearing Technique for Easy-to-Use 3D Cell Culturing and True 3D Characterization. 

Tuesday, February 6th, 5:00 - 6:00 PM - 1053-D- Dehydration Free High Throughput 3D Cell Culture Clearing and 3D Confocal Imaging.

Visikol at SLAS