Come Check Out Visikol's Science Exchange Webinar on Advanced Imaging and Image Analysis Services

Three major opportunities for improvement in early-stage in vitro and animal model studies are to improve the predictive capability of in vitro models themselves, the extraction of more complete data from cell cultures and animal models, and to shift from qualitative histological evaluation to a quantitative digital pathology approach. Through this webinar, Visikol will focus its discussion on the use of 3D cell culture models, the application of 3D tissue imaging for studying complex phenomena such as angiogenesis and how digital pathology and machine learning can be used to extract quantitative data from tissues.

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Michael Johnson
Visikol Keynote Presentor at LabRoots Cell Biology 2018 - Sept 26 - 3PM EST

With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-environment; showing improved predictive utility for assessing drug efficacy and/or toxicity when compared to traditional 2D monolayer models. High-content analysis/screening (HCA/HCS) also plays a major role in drug screening, but one of the unique challenges of evaluating 3D-CCMs (i.e. spheroids, organoids, micro-tissues, organs-on-a-chip) is their opacity and thickness that limit optical imaging to only the outermost layers (~20=30 microns).

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Michael Johnson