Researchers Use HUREL Micro Livers to Study Ulotaront
Ulotaront (SEP-363856) is a trace amine-associated receptor 1 (TAAR1) agonist with 5-hydroxytryptamine type 1A (5-HT1A) and is in phase [...]
Implications of Using a Micro Liver Assay in Research
HUREL cells are micro liver coculture of liver cells consisting of 30,000 liver cells in each well of a [...]
Emerging Trends in Therapeutics Based on Epigenetics
Epigenetic mechanisms regulate gene transcription and genomic stability and maintain normal cell growth, development, and differentiation. At the molecular [...]
Cell Viability and Cytotoxicity Assessment
When Pharmaceutical companies are developing new therapeutics, it is essential to test the viability and cytotoxicity of those compounds [...]
Celebrating HUREL’s One-Year Anniversary
Today marks the one-year anniversary of Visikol acquiring the HUREL® portfolio of Micro Liver products and services. We have [...]
An Overview of Complementary DNA Synthesis
Many biological processes, such as gene cloning and gene expression analysis using real-time polymerase chain reaction (qPCR) and high-throughput [...]
LC-MS/MS Quantification of the Methylation Status of Clinical Samples of NASH Liver Tissues
Nonalcoholic fatty liver disease (NAFLD) is a common hepatic disorder in individuals who drink little or no alcohol. A [...]
Quantification of global m6A RNA methylation levels by LC-MS/MS
Epigenetics is the study of heritable changes in gene expression without any alternation in the DNA sequence. The main [...]
Using Cell Painting for Morphological Changes
To understand the cytological profiles of cells, a cell painting assay can be used to identify the difference in [...]
An Example of Multi-Dimensional Image Analysis: Advanced 3D Cell Counting
As multi-dimensional imaging becomes more accessible to many areas of research, the need for 3D analysis has also increased. [...]