General clearing agent for plant tissues
Improved skeletal visualization for DART studies
Adding a third dimension to histology
Clearing for gross visualization of animal tissues
Optical computed tomography with Clara™
Whole tissue optical imaging with Visikol
Visikol® enables whole mount immuno-histochemistry (IHC) like never before. Obtain whole-tissue protein maps using whole mount IHC followed by clearing with Visikol. IHC prior to clearing with Visikol allows labeling of antigendistribution in whole tissues with microscopic techniques, eliminating the need for sectioning, reconstruction, and stereology.
Fluorescence in situ Hybridization
Fluorescence in situ hybridization (FISH) is a powerful labeling technique to identify mRNA or DNA in tissues. Traditional FISH is limited to thin tissue sections, but with Visikol, tissue-wide gene expression can be accomplished with ease. Visikol coupled to FISH is a powerful tool for study protein distribution in tissues.
Using a combination of fluorescent sensors and labels, reporter genes, immunohistochemistry, and fluorescent microscopy in conjunction with Visikol tissue clearing, disease-state tissues can be rapidly phenotyped with ease. Optical clearing techniques have made huge waves in the literature, but none are as easy and safe as Visikol.