Visikol HISTO is reversible
Visikol® HISTO™ preserves tissues! Tissue clearing techniques like CLARITY, SeeDB, BABB and 3DISCO irreversibly change the cellular structure of tissues, since they rely on removal of lipid structures and/or hydration of protein structure.
Say "so long" to stereology! With Visikol HISTO, traditional 2D H&E processing can be completed after 3D imaging, so you can choose exactly which sections are of interest, before the tissue is even embedded.
Obtain 3D image stacks and 2D H&E slides from the same sample! You don't have to choose between 3D imaging and your conventional tissue-imaging workflow, Visikol fits right in so you can get the most out of each specimen!
H&E sections after clearing with Visikol HISTO
Brain tissue (mouse) - H&E and GFAP-labeled IHC sections of mouse brain tissue after clearing with Visikol HISTO
Kidney (mouse) - H&E section of mouse kidney following clearing and reversal.
Lung (mouse) - H&E section of mouse lung following clearing and reversal.
Liver (mouse) - H&E section of a mouse liver following clearing and reversal.
Placenta tissue (human) - H&E sections of human placenta tissue after clearing reversal.