Steatosis and Phospholipidosis Landing Page2019-08-20T16:28:20-05:00

Steatosis and Phospholipidosis Assay

Rapidly assess compounds in vitro for hepatotoxicity

Hepatotoxicity and Drug Compounds

Hepatotoxicity is one of the leading causes of attrition in drug development pipelines. Steatosis and phospholipidosis are disorders of the liver which cause abnormal retention of triglycerides and phospholipids, respectively. These conditions can be induced by hepatotoxic drug compounds, and can lead to delays in the drug development process if not properly assessed and mitigated. In vitro assessment of drug-induced steatosis and phospholipidosis is an important part of the screening process.

With Visikol, you can pursue the cutting edge of in vitro models, bioimaging, and tissue analysis to exploit the wealth of information contained within every experiment. The unique approach we take to conducting drug discovery research allows our clients to get more out of their in vitro screening campaigns, giving more accurate and more reliable information for making better informed decisions early in the pipeline.

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3D cell culture models better mimic the in vivo microenvironment and better mimic response to drug treatment, giving you more reliable data earlier in the discovery process.

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Using high content confocal imaging, assay multiple endpoints simultaneously, giving you more data about your compounds faster.

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Our expert team processes images and analyzes data, delivering actionable insights in an easy-to-read report, so you can make decisions and push forward your drug discovery efforts.

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To learn more about this assay and how to start working with us today, click below.

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In Vitro Assay Services Specializing in 3D cell culture assays, Visikol performs in vitro assays for drug screening and toxicity assessment using high content confocal microscopy, ELISA, and other luminescence and fluorescence plate reader assays.
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Tissue Imaging and Analysis Services Using immunolabeling, tissue clearing, and confocal microscopy, we are able to transform tissues into three-dimensional data sets for sophisticated quantitative histological analysis.
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Digital Pathology and Slide Analysis We help our Clients shift their histopathology analysis efforts from a qualitative, human-driven approach to a quantitative, digital approach. We have worked with clients on projects ranging from simple slide digitization and cell counting to developing custom-built, 21 CFR Part 11 compliant tissue classification algorithms and software for use in a clinical setting.
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Custom Drug Discovery Solutions The Visikol team is comprised of experts in assay development, imaging, image analysis and advanced in vitro models. We can work with you to develop customized research programs to address the most complex drug discovery and development problems. We offer implementation services so clients can in-source our custom-developed assays.
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3D Cell Culture Models As experts in 3D cell culture model generation and assessment, we will find a model to match your needs. Visikol provides standardized and custom 3D cell culture models to clients that meet specific cost, throughput and bio-relevancy requirements.
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